Pirfenidone (S-7701, AMR-69) is an inhibitor for TGF-? production and TGF-? stimulated collagen production, reduces production of TNF-? and IL-1?, and also has anti-fibrotic and anti-inflammatory properties. Pirfenidone attenuates chemokine (CC motif) ligand-2 (CCL2) and CCL12 production with anti-fibrotic activity. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.